• 咨询热线
    客服服务热线 13671568941/15317326293
  • 在线咨询
  • 微信客服
    微信客服
  • 公众号
    扫码关注公众号

Rilmenidine Phosphate

CAS No. 85409-38-7

Rilmenidine Phosphate ( —— )

产品货号. M19181 CAS No. 85409-38-7

Rilmenidine Phosphate 是一种选择性 I(1) 咪唑啉受体激动剂,用于治疗高血压。

纯度: >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
规格 价格/人民币 库存 数量
5MG ¥648 有现货
10MG ¥1126 有现货
25MG ¥2252 有现货
50MG ¥3556 有现货
100MG ¥5338 有现货
500MG ¥11097 有现货
1G 获取报价 有现货

生物学信息

  • 产品名称
    Rilmenidine Phosphate
  • 注意事项
    本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
  • 产品简述
    Rilmenidine Phosphate 是一种选择性 I(1) 咪唑啉受体激动剂,用于治疗高血压。
  • 产品描述
    Rilmenidine Phosphate is a selective I(1) imidazoline receptor agonist, used to treat hypertension.(In Vitro):Rilmenidine provides antihypertensive efficacy comparable with that of diuretics, beta-blockers, calcium channel blockers, and angiotensin-converting enzyme (ACE) inhibitors.Rilmenidine phosphate (25-100 μM; 24 hours) inhibits K562 cell proliferation.(In Vivo):Rilmenidine phosphate-treated N171-82Q mice (i.p.; 4-times a week) displays significant improved forelimb grip strength and all limbs grip strength from 12 to 22 weeks of age.Rilmenidine phosphate decreases levels of mutant huntingtin.
  • 体外实验
    Rilmenidine provides antihypertensive efficacy comparable with that of diuretics, beta-blockers, calcium channel blockers, and angiotensin-converting enzyme (ACE) inhibitors.Rilmenidine phosphate (25-100 μM; 24 hours) inhibits K562 cell proliferation. Cell Proliferation Assay Cell Line:K562 cells Concentration:25, 50, 100 μM Incubation Time:24 hours Result:Dose-dependently inhibited K562 colony formation.
  • 体内实验
    Rilmenidine phosphate-treated N171-82Q mice (i.p.; 4-times a week) displays significant improved forelimb grip strength and all limbs grip strength from 12 to 22 weeks of age.Rilmenidine phosphate decreases levels of mutant huntingtin.
  • 同义词
    ——
  • 通路
    Others
  • 靶点
    Other Targets
  • 受体
    I(1) imidazoline receptor
  • 研究领域
    Others-Field
  • 适应症
    ——

化学信息

  • CAS Number
    85409-38-7
  • 分子量
    278.24
  • 分子式
    C10H19N2O5P
  • 纯度
    >98% (HPLC)
  • 溶解度
    In Vitro:?H2O : 83.33 mg/mL (299.49 mM)
  • SMILES
    C1CC1C(C1CC1)NC1=NCCO1.OP(=O)(O)O
  • 化学全称
    ——

运输与储存

  • 储存条件
    (-20℃)
  • 运输条件
    With Ice Pack
  • 稳定性
    ≥ 2 years

参考文献

1.Srdic-Rajic T, et al.Eur J Pharm Sci. 2016 Jan 1;81:172-80.
产品手册
关联产品
  • 2-Fluoroadenosine

    2-Fluoroadenosine 是淋巴细胞介导的细胞溶解的有效抑制剂。

  • PTD-p65-P1 Peptide

    PTD-p65-P1 Peptide is a nuclear transcription factor NF-kappaB inhibitor, composed of a membrane-translocating peptide sequence generated from antennapedia (PTD) conjugated with p65-P1, which selectively inhibits activation induced by various inflammatory stimuli. PTD-p65-P1 suppressed NF-kappaB activation induced by lipopolysaccharide, interleukin-1, okadaic acid, phorbol 12-myristate 13-acetate, H(2)O(2), and cigarette smoke condensate as well as that induced by TNF.

  • Violanone

    Violanone is a natural product for research related to life sciences.